发明名称 |
METHOD OF TREATING DIABETES |
摘要 |
Methods are provided for treating diabetes, lowering plasma level of HbA1c, glucose plasma levels, total cholesterol plasma level, and/or triglyceride plasma level while increasing HDL cholesterol levels and delaying onset of diabetic retinopathy in a diabetic, pre-diabetic, or non-diabetic mammal while minimizing undesirable side effects. |
申请公布号 |
US2014378465(A1) |
申请公布日期 |
2014.12.25 |
申请号 |
US201414476650 |
申请日期 |
2014.09.03 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
JERLING MARKUS;WOLFF ANDREW A. |
分类号 |
A61K31/495 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating diabetes in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of ranolazine, which is N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide, as a racemic mixture or an isomer thereof, or a pharmaceutically acceptable salt thereof, wherein the patient has a HbA1c level higher than about 7.5%. |
地址 |
Foster City CA US |