ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS

摘要

The present invention provides compounds of formula (I) wherein P is P0, heterocyclyl or heterocyclyl substituted by one to five Z formula (II); Y1, Y2, Y3 and Y4 are independently of each other C—H, C—R5, or nitrogen; G1 is oxygen or sulfur; X4 is C1-C8 haloalkyl; R4 is aryl or aryl substituted by one to five R9, or heteroaryl or heteroaryl substituted by one to five R9; and R1, R2, R4, R5, R9 and Z are as defined in the claims. The invention also provides compositions comprising the compounds of formula (I), intermediates useful in the preparation of compounds of formula (I) and methods of using the compounds of formula (I) to control insects, acarines, nematodes or molluscs.;

主权项

1. A compound of formula (I)wherein
P is P0, heterocyclyl or heterocyclyl substituted by one to five Z; Y1, Y2, Y3 and Y4 are independently of each other C—H, C—R5, or nitrogen; G1 is oxygen or sulfur; R1 is hydrogen, C1-C8alkyl, C1-C8alkoxy-, C1-C8alkylcarbonyl-, or C1-C8alkoxycarbonyl-; R2 is C1-C8alkyl or C1-C8alkyl substituted by one to five R6, C3-C10cycloalkyl or C3-C10cycloalkyl substituted by one to five R7, aryl-C1-C4alkylene- or aryl-C1-C4alkylene- wherein the aryl moiety is substituted by one to five R8, heterocyclyl-C1-C4alkylene- or heterocyclyl-C1-C4alkylene- wherein the heterocyclyl moiety is substituted by one to five R8, aryl-N(R20)— or aryl-N(R20)— wherein the aryl moiety is substituted by one to five R8, heterocyclyl-N(R20)— or heterocyclyl-N(R20)— wherein the heterocyclyl moiety is substituted by one to five R8, aryl or aryl substituted by one to five R8, heterocyclyl or heterocyclyl substituted by one to five R8, C1-C8alkylaminocarbonyl-C1-C4 alkylene, C1-C8haloalkylaminocarbonyl-C1-C4 alkylene, C3-C8cycloalkyl-aminocarbonyl-C1-C4 alkylene, C1-C8alkylaminocarbonyl-, C1-C8haloalkylaminocarbonyl, C3-C8cycloalkyl-aminocarbonyl, C1-C6alkyl-O—N═CH—, C1-C6haloalkyl-O—N═CH—; or R1 and R2 together represent group A G2 is O(R13), N(R14)(R15) or S(R16); G3 is N(R17)(R18) or S(R19); X4 is C1-C8haloalkyl; R4 is aryl or aryl substituted by one to five R9, or heteroaryl or heteroaryl substituted by one to five R9; each R5 is independently halogen, cyano, nitro, C1-C8alkyl, C1-C8haloalkyl, C1-C8alkenyl, C1-C8haloalkenyl, C1-C8alkynyl, C1-C8haloalkynyl, C3-C10cycloalkyl, C1-C8alkoxy-, C1-C8haloalkoxy-, C1-C8alkylthio-, C1-C8haloalkylthio-, C1-C8alkylsulfinyl-, C1-C8haloalkylsulfinyl-, C1-C8alkylsulfonyl-, or C1-C8haloalkylsulfonyl-; or two R5 on adjacent carbon atoms together form a —CH═CH—CH═CH— bridge; each R6 is independently halogen, cyano, nitro, hydroxy, amino, C1-C8alkylamino, (C1-C8alkyl)2amino, C1-C8alkylcarbonylamino, C1-C8haloalkylcarbonylamino, C1-C8alkoxy-, C1-C8haloalkoxy-, aryloxy or aryloxy substituted by one to five R10, aryloxy-C1-C4alkylene or aryloxy-C1-C4alkylene wherein the aryl moiety is substituted by one to five R10, C1-C8alkylcarbonyl-, C1-C8alkoxycarbonyl-, mercapto, C1-C8alkylthio-, C1-C8haloalkylthio-, C1-C8alkylsulfinyl-, C1-C8haloalkylsulfinyl-, C1-C8alkylsulfonyl-, C1-C8haloalkylsulfonyl-, aryl-C1-C4alkylthio or aryl-C1-C4alkylthio wherein the aryl moiety is substituted by one to five R10; each R7 is independently halogen, C1-C8alkyl, C1-C8alkenyl, C1-C8alkynyl, C1-C8alkyl-O—N═, C1-C8haloalkyl-O—N═; C1-C8alkoxy, C1-C8akoxycarbonyl; each R8 is independently halogen, cyano, nitro, oxo, C1-C8alkyl, C1-C8haloalkyl, C1-C8cyanoalkyl, C2-C8alkenyl, C2-C8haloalkenyl, C2-C8alkynyl, C2-C8haloalkynyl, C3-C10cycloalkyl, C3-C10cycloalkyl-C1-C4alkylene, hydroxy, C1-C8alkoxy-, C1-C8haloalkoxy-, mercapto, C1-C8alkylthio-, C1-C8haloalkylthio-, C1-C8alkylsulfinyl-, C1-C8haloalkylsulfinyl-, C1-C8alkylsulfonyl-, C1-C8haloalkylsulfonyl-, C1-C8alkylaminosulfonyl, (C1-C8alkyl)2aminosulfonyl-, C1-C8alkylcarbonyl-, C1-C8alkoxycarbonyl-, aryl or aryl substituted by one to five R10, heterocyclyl or heterocyclyl substituted by one to five R10, aryl-C1-C4alkylene or aryl-C1-C4alkylene wherein the aryl moiety is substituted by one to five R10, heterocyclyl-C1-C4alkylene or heterocyclyl-C1-C4alkylene wherein the heterocyclyl moiety is substituted by one to five R10, aryloxy or aryloxy substituted by one to five R10, aryloxy-C1-C4alkylene or aryloxy-C1-C4alkylene wherein the aryl moiety is substituted by one to five R10; each R9 is independently halogen, cyano, nitro, C1-C8alkyl, C1-C8haloalkyl, C2-C8alkenyl, C2-C8haloalkenyl, C2-C8alkynyl, C2-C8haloalkynyl, hydroxy, C1-C8alkoxy-, C1-C8haloalkoxy-, mercapto, C1-C8alkylthio-, C1-C8haloalkylthio-, C1-C8alkylsulfinyl-, C1-C8haloalkylsulfinyl-, C1-C8alkylsulfonyl-, C1-C8haloalkylsulfonyl-, C1-C8alkylcarbonyl-, C1-C8alkoxycarbonyl-, aryl or aryl substituted by one to five R10, or heterocyclyl or heterocyclyl substituted by one to five R10; each R10 is independently halogen, cyano, nitro, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy-, or C1-C4haloalkoxy-; each Z is independently halogen, C1-C12alkyl or C1-C12alkyl substituted by one to five R6, nitro, C1-C12alkoxy or C1-C12alkoxy substituted by one to five R6, cyano, C1-C12alkylsulfinyl, C1-C12alkylsulfonyl, C1-C12haloalkylsulfinyl, C1-C12haloalkylsulfonyl, hydroxyl or thiol; R13, R16 and R19 are independently C1-C4 alkyl; R14, R15, R17, and R18 are independently hydrogen or C1-C4 alkyl; R20 is hydrogen or C1-C4 alkyl; or a salt or N-oxide thereof.