| 发明名称 |
RAF DIMERS AND USES THEREOF |
| 摘要 |
Disclosed herein are mutated RAF and KSR nucleic acids and polypeptides. Also disclosed are methods of using the mutated RAF and KSR to inhibit the dimerization of RAF/RAF and RAF/KSR. Also disclosed are methods of using the mutated RAF and KSR to screen for inhibitors of dimerization. |
| 申请公布号 |
US2014378324(A1) |
申请公布日期 |
2014.12.25 |
| 申请号 |
US201314135934 |
申请日期 |
2013.12.20 |
| 申请人 |
MOUNT SINAI HOSPITAL ;UNIVERSITE DE MONTREAL |
发明人 |
LAVOIE HUGO;Sahmi Malha;Therrien Marc;Rajakulendran Thanashan;Sicheri Frank |
| 分类号 |
C12Q1/66;G01N33/58 |
主分类号 |
C12Q1/66 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
Toronto CA |
