Treatment of Neurodegenerative Diseases Through Inhibition of HSP90

摘要

Treatment of neurodegenerative diseases is achieved using small molecule purine scaffold compounds that inhibit Hsp90 and that possess the ability to cross the blood-brain barrier or are other wise delivered to the brain.

主权项

1. A method for treatment of neurodegenerative disease, comprising the step of administering to an individual in need of such treatment a therapeutically effective amount of a purine scaffold compound that inhibits Hsp90, wherein the compound and the mode of administration are selected such that the compound is delivered to the brain.