发明名称 |
Novel P. Pastoris Pastoris Promoters, and the Use Thereof to Direct Expression of Proteins in Yeast, Preferably Using a Haploid Mating Strategy |
摘要 |
Novel promoters which are derived from P. pastoris pastoris which are inducible or repressible under specific growth conditions are provided. These promoters are useful for regulating the expression of a desired structural gene, e.g., a mammalian polypeptide. Particularly preferred is the use of these novel promoters to regulate gene expression in polyploidal yeast such as diploidal P. pastoris produced by mating or spheroplast fusion. |
申请公布号 |
US2014377802(A1) |
申请公布日期 |
2014.12.25 |
申请号 |
US201414323678 |
申请日期 |
2014.07.03 |
申请人 |
ALDERBIO HOLDINGS LLC |
发明人 |
CREGG James M.;TOLSTORUKOV Ilya I. |
分类号 |
C12N9/88;C12N15/81;C07K16/28 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Las Vegas NV US |