| 发明名称 |
PROCESS FOR THE PREPARATION OF PROTECTED L-ALANINE DERIVATIVES |
| 摘要 |
The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators. |
| 申请公布号 |
US2014378701(A1) |
申请公布日期 |
2014.12.25 |
| 申请号 |
US201414478253 |
申请日期 |
2014.09.05 |
| 申请人 |
Janssen Pharmaceutica, N.V. |
发明人 |
Anzalone Luigi;Feibush Penina;Villani Frank J. |
| 分类号 |
C07C231/06;C07C233/65 |
主分类号 |
C07C231/06 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for the preparation of a compound of formula (II-B)or a pharmaceutically acceptable salt thereof; comprisingreacting a compound of formula (I-B) with an oxidizing agent; in the presence of an inorganic base; in a third organic solvent; to yield the corresponding compound of formula (II-B). |
| 地址 |
Beerse BE |
