SYNTHESIS OF FREE RADICAL POLMERIZABLE ETHYLENICALLY UNSATURATED POLOXAMERS AND POLOXAMINES

摘要

A new synthetic method of forming free radical polymerizable end terminal functionalized poloxamers and poloxamines in commercial scale batches which uses a binary system of inhibitors to eliminate the formation of high molecular weight impurities. It has also been surprisingly discovered that the inorganic impurities formed during the commercial scale synthetic process are removed by the use of resin materials.