| 摘要 |
[Problem] The objective of the present invention is to provide an economically advantageous and industrially suitable method for manufacturing a 2-amino-2-hydroxyimino-N-alkoxy acetoimidoyl cyanide represented by general formula (3). [Solution] The present invention enables the safe, high-yield manufacture of the compound represented by general formula (3) (wherein R represents a C3-C6 alkyl group), that is a 2-amino-2-hydroxyimino-N-alkoxy acetoimidoyl cyanide, by reacting the malononitrile represented by formula (1) with an alkali metal salt of nitrous acid in the presence of a protonic acid, and then, after reacting the product with a C3-C6 alkyl halide in the presence of a phase transfer catalyst, reacting the obtained compound represented by novel general formula (2) (wherein R is the same as above), that is a 2-alkoxyimino propane dinitrile, with a hydroxyl amino compound. |
