发明名称 |
DIMETHYLARGININE DIMETHYLAMINOHYDROLASE INHIBITORS AND METHODS OF USE THEREOF |
摘要 |
<p>The present disclosure provides DDAH modulators. Thus, the present disclosure provides a method of treating a patient suffering from a disorder characterized by excessive NO production and/or elevated DDAH activity, the method comprising administering to said patient an effective amount of a compound of one of formulae I-X. The present disclosure also provides a pharmaceutical composition comprising a compound of one of formulae I-X.</p> |
申请公布号 |
EP2814488(A1) |
申请公布日期 |
2014.12.24 |
申请号 |
EP20130749899 |
申请日期 |
2013.02.13 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
GHEBREMARIAM, YOHANNES, TSEGAI;COOKE, JOHN, P. |
分类号 |
A61K31/4184;A61K31/4188;A61P1/16;A61P9/00;A61P11/00;A61P17/00;A61P19/00;A61P21/00;A61P27/06;A61P43/00 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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