| 摘要 |
<p>The ophthalmic drug delivery vehicles which include from about 1 % to about 15% w/v nonionic surfactant, one or more non-Newtonian high blend viscosity enhancing, non-gelling agents and from about 0.025% to about 0.90% sodium chloride. Particularly, formulations that have the non-Newtonian characteristics at 37 degrees C of creating a viscosity increase in ratio of at least about 3:1 within 1-2 seconds at the low shear force between blinks and drops within the fraction of a second to the high shear force of each blink, which on dilution maintain a viscosity of about 10 cps or greater during each blink and which do not cause excessive stinging or discomfort, are disclosed.</p> |
