The purpose of the present invention is to provide a novel therapeutic means for curing HBV infections. Provided is an HBV-specific artificial DNA nuclease comprising: a transcription activator-like effector (TALE) derived from Xanthomonas bacterium modified so as to specifically bond with HBV DNA; and a sequence-independent endonuclease.
申请公布号
WO2014204014(A1)
申请公布日期
2014.12.24
申请号
WO2014JP67092
申请日期
2014.06.20
申请人
TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE;PHOENIXBIO CO., LTD.
