Apparatus and methods for inserting a medicament into a body cavity are described. The apparatus (100) comprises an elongate tube (110) with a plunger rod (150) therein. The plunger rod (150) has at least one projection (158) which cooperatively interacts or engages with at least one discontinuity (124) on the inside of the elongate tube (110) so that proximal movement of the plunger rod (150) with respect to the elongate tube (110) expels the medicament into the body cavity.