COMPOSITIONS AND METHODS FOR MODULATING GENE EXPRESSION
摘要
<p>Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of a target gene. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of a target gene. Methods for modulating expression of a target gene using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of a target gene.</p>
申请公布号
WO2013173637(A8)
申请公布日期
2014.12.24
申请号
WO2013US41437
申请日期
2013.05.16
申请人
RANA THERAPEUTICS, INC.;THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL
发明人
KRIEG, ARTHUR, M.;SUBRAMANIAN, ROMESH;MCSWIGGEN, JAMES;LEE, JEANNIE, T.