发明名称 |
FORMULATIONS AND METHODS FOR THE TREATMENT OR PROPHYLAXIS OF PRE-MCI AND/OR PRE-ALZHEIMER'S CONDITIONS |
摘要 |
<p>In certain embodiments the methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's cognitive dysfunction, and/or preventing or delaying the progression of a pre-Alzheimer's condition or cognitive dysfunction to Alzheimer's disease, and/or of promoting the processing of amyloid precursor protein (APP) by the non-amyloidogenic pathway are provided. In certain embodiments the methods involve administering, or causing to be administered, to a subject in need thereof certain formulations comprising or more active agent(s) selected from the group consisting of tropisetron disulfiram, honokiol, nimetazepam, and/or derivatives or analogs thereof.</p> |
申请公布号 |
EP2814491(A1) |
申请公布日期 |
2014.12.24 |
申请号 |
EP20130749359 |
申请日期 |
2013.02.15 |
申请人 |
BUCK INSTITUTE FOR RESEARCH ON AGING |
发明人 |
JOHN, VARGHESE;BREDESEN, DALE E.;TZANNIS, STELIOS |
分类号 |
A61K31/439;A61K9/00;A61K9/20;A61K9/22;A61K31/05;A61K31/145;A61K31/46;A61K31/5513;A61K31/724;A61K47/36;A61K47/40;A61K47/48;A61P25/28 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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