摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a solid preparation which contains ketotifen or its salts and has improved disintegration and dissolution. <P>SOLUTION: The solid preparation comprises (a) ketotifen or its salts, (b) a disintegrator, and (c) an organic acid or its salt. Croscarmellose sodium, crospovidone or low substituted hydroxypropylcellulose are used as the disintegrator. Citric acid, malic acid, tartaric acid, ascorbic acid, or succinic acid are used as the organic acid. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |