发明名称 COMPOSITIONS COMPRISING AT LEAST ONE POLYMETHOXYFLAVONE, FLAVONOID, LIMINOID, AND/OR TOCOTRIENOL USEFUL IN COMBINATION THERAPIES FOR TREATING DIABETES
摘要 Compositions comprising select natural products have been found to be useful as supplements to known medicaments for treating elevated blood glucose, HbAlc, blood pressure and cholesterol levels in persons suffering from metabolic syndrome, insulin resistance, and type 2 diabetes. The natural products of interest include polymethoxyflavones, flavonoids, liminoids, and tocotrienols, while the known medicaments include metformin. In preferred embodiments, the natural products are polymethoxyflavones found in citrus plants, such as nobiletin, tangeretin, and synephrin. Use of the natural product of interest will preferably result in HbAlc ≤ 7%, LDL-C ≤ 100 mg/dL, total cholesterol ≤ 200 mg/dL; and systolic blood pressure ≤ 130 mm Hg.
申请公布号 WO2014203059(A1) 申请公布日期 2014.12.24
申请号 WO2014IB01069 申请日期 2014.06.13
申请人 KGK SYNERGIZE, INC. 发明人 GUTHRIE, NAJLA
分类号 A61K31/352;A61K31/137;A61K31/155;A61K31/355;A61K36/48;A61K36/752;A61P3/10;C07D311/30 主分类号 A61K31/352
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