发明名称 |
DEVICES, COMPOSITIONS AND METHODS FOR IMAGING WITH RAMAN SCATTERING |
摘要 |
Methods, systems and computer-accessible medium for imaging a living cell or a living organism with bond-edited compounds using stimulated Raman scattering are disclosed. The method comprises the steps of introducing one or more bond-edited compounds into a live cell or a living organism, and detecting a vibrational tag in the cell or organism with stimulated Raman scattering. Also disclosed are methods for detecting a disease condition in a subject methods for monitoring treatment for a disease condition, methods for screening an agent, methods for tracing a cellular process in a live cell using bond-edited compounds in combination with stimulated Raman scattering. Also disclosed are a composition for labeling a target cell with at least one bond-edited compound and devices for imaging bond-edited compounds by stimulated Raman scattering. |
申请公布号 |
WO2014205074(A2) |
申请公布日期 |
2014.12.24 |
申请号 |
WO2014US42936 |
申请日期 |
2014.06.18 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
MIN, WEI;WEI, LU;CHEN, ZHIXING;HU, FANGHAO;SHEN, YIHUI |
分类号 |
A61K49/00 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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地址 |
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