| 摘要 |
The present invention provides a method of determining prognosis of cancer in a subject, comprising: detecting the level of LARP1 protein in a serum or plasma sample from a subject; and comparing the level of LARP1 protein in said sample with the level of LARP1 protein in a control sample, wherein an elevated level of LARP1 protein in said serum or plasma sample from said subject compared to the level of LARP1 protein in said control sample is indicative of poor prognosis of said cancer. The present invention also provides related methods of diagnosing cancer in a subject as well as methods of determining whether a subject responds to a drug that acts on the PI3K/AKT/m TOR pathway based on the level of LARP1 protein in a serum or plasma sample from a subject, and associated methods of treating cancer. |
