| 发明名称 |
Anticancer steroidal lactones unsaturated in position 7 (8) |
| 摘要 |
<p>The disclosure relates to a compound of general formula (I), wherein R1-R17 and the ------ line are as defined in the specification. Specific examples of these steroidal lactones were isolated from the organism Mycale (Aegogropila) crassissima and are given the names Aegomycin A - H. The disclosure also relates to pharmaceutical compositions comprising these compounds and their use in the treatment of cancer.</p> |
| 申请公布号 |
NZ603261(A) |
申请公布日期 |
2014.12.24 |
| 申请号 |
NZ20110603261 |
申请日期 |
2011.04.26 |
| 申请人 |
PHARMA MAR S.A. |
发明人 |
REYES BENITEZ JOSE FERNANDO;FRANCESCH SOLLOSO ANDRES;CUEVAS MARCHANTE MARIA DEL CARMEN;FERNANDEZ RODRIGUEZ ROGELIO |
| 分类号 |
C07J19/00;A61K8/63;A61K31/585;A61P35/00;C07J17/00;C07J71/00 |
主分类号 |
C07J19/00 |
| 代理机构 |
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