5-membered ring heteroaromatic derivatives having NPY Y5 receptor antagonistic activity

摘要

This invention provides new compounds having NPY Y5 antagonistic activity. The present inventors found that a compound of the formula (I):;
wherein R1 is substituted or unsubstituted alkyl or the like; p, q and r are each independently 0 or 1; ring A is oxadiazole; and R2 is substituted or unsubstituted alkyl or the like, has NPY Y5 antagonistic activity.

主权项

1. A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1 is substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl or substituted amino, p is 1, and q and r are 0, a group of formula: is a group of formula:  and R2 is substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocyclyl.