发明名称 NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO{,2-@}[1,4]-BENZODIAZEPINES AND 6H-PYRROLO[1,2@[1,4]BENZODIAZEPINES SUSBSTITUTED WITH BICYCLIC BENZENE DERIVATIVES
摘要 The present invention is concerned with novel antifungal 5,6-dihydro-4H-pyrrolo-[1,2-a][1,4]benzodiazepines and 6H-pyrrolo[1,2-a][1,4]benzodiazepines substituted with bicyclic benzene derivatives of Formula (I) wherein R1, R2, R3, R4, R5, R6 and R7 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
申请公布号 ZA201304577(B) 申请公布日期 2014.12.23
申请号 ZA20130004577 申请日期 2013.06.20
申请人 JANSSEN PHARMACEUTICA N.V. 发明人 MEERPOEL LIEVEN;DE WIT KELLY;MAES LOUIS JULES ROGER MARIE
分类号 A61K;A61P;C07D 主分类号 A61K
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