Fusarisetin compounds, and use thereof

摘要

The present invention relates to novel fusarisetin compounds separated from Fusarium sp. FN080326 and having an anticancer activity, and to the use thereof. In detail, novel fusarisetin compounds separated and purified from Fusarium sp. FN080326, which is in turn separated from a soil sample, have an inhibitory activity on the proliferation and transfer of cancer cells such as breast cancer cells, liver cancer cells or myeloid leukemic cells. Therefore, the compounds can be effectively used for anticancer compositions containing the compounds as active ingredients.

主权项

1. A compound of formula 3 or pharmaceutically acceptable salts thereof: wherein, R1-6 are independently H, methyl, ethyl, propyl, isopropyl, butyl, isobutyl, acetyl, benzyl, halogen atom, OH, or carboxyl group, and contain isomers at all asymmetric carbons.