发明名称 S100A4 antibodies and therapeutic uses thereof
摘要 The invention relates to antibodies against S100A4, methods for the preparation of these antibodies, pharmaceutical compositions comprising these antibodies, and therapeutic and diagnostic uses thereof.
申请公布号 US8916152(B2) 申请公布日期 2014.12.23
申请号 US201113704333 申请日期 2011.06.14
申请人 Lykera Biomed SA 发明人 Hernandez Miguez Jose Luis;Adan Plana Jaume;Martinez Escola Josep Maria;Masa Alvarez Marc;Messeguer Peypoch Ramon;Mitjans Prat Francesc;Dakhel Plaza Sheila;Coll Manzano Antonio;Hervas Villegas Rosa Ma;Calvis Calpe Carme;Padilla Garcia Laura;Roque Navarro Lourdes Tatiana;Barbera Ferrando Laura;Rivas Canas Manuel;Gomez Casajus Luis Angel
分类号 C07K16/18;A61K39/395;C12P21/08;A61K38/00;A61K45/06;G01N33/68;C07K16/30;A61K39/00 主分类号 C07K16/18
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP
主权项 1. A specific anti-S100A4 antibody having anti-angiogenic activity or a fragment thereof showing at least 50% of the anti-angiogenic activity of said antibody wherein the antibody is produced by a hybridoma selected from the group consisting of: ECACC 10022401, ECACC 11051801, ECACC 11051802, ECACC 11051803 and ECACC 11051804.
地址 Terrasa ES