发明名称 |
S100A4 antibodies and therapeutic uses thereof |
摘要 |
The invention relates to antibodies against S100A4, methods for the preparation of these antibodies, pharmaceutical compositions comprising these antibodies, and therapeutic and diagnostic uses thereof. |
申请公布号 |
US8916152(B2) |
申请公布日期 |
2014.12.23 |
申请号 |
US201113704333 |
申请日期 |
2011.06.14 |
申请人 |
Lykera Biomed SA |
发明人 |
Hernandez Miguez Jose Luis;Adan Plana Jaume;Martinez Escola Josep Maria;Masa Alvarez Marc;Messeguer Peypoch Ramon;Mitjans Prat Francesc;Dakhel Plaza Sheila;Coll Manzano Antonio;Hervas Villegas Rosa Ma;Calvis Calpe Carme;Padilla Garcia Laura;Roque Navarro Lourdes Tatiana;Barbera Ferrando Laura;Rivas Canas Manuel;Gomez Casajus Luis Angel |
分类号 |
C07K16/18;A61K39/395;C12P21/08;A61K38/00;A61K45/06;G01N33/68;C07K16/30;A61K39/00 |
主分类号 |
C07K16/18 |
代理机构 |
McCarter & English, LLP |
代理人 |
McCarter & English, LLP |
主权项 |
1. A specific anti-S100A4 antibody having anti-angiogenic activity or a fragment thereof showing at least 50% of the anti-angiogenic activity of said antibody wherein the antibody is produced by a hybridoma selected from the group consisting of:
ECACC 10022401, ECACC 11051801, ECACC 11051802, ECACC 11051803 and ECACC 11051804. |
地址 |
Terrasa ES |