发明名称 Pharmaceutical compositions comprising POH derivatives
摘要 The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.
申请公布号 US8916545(B2) 申请公布日期 2014.12.23
申请号 US201213566731 申请日期 2012.08.03
申请人 Neonc Technologies Inc. 发明人 Chen Thomas;Levin Daniel;Pupalli Satish
分类号 A61K47/48;C07D207/26;C07D487/04;A61N5/10;A61K45/06;A61K31/415;C07D231/12 主分类号 A61K47/48
代理机构 Ascenda Law Group PC 代理人 Ascenda Law Group PC
主权项 1. A composition comprising a perillyl alcohol carbamate, wherein the perillyl alcohol carbamate comprises perillyl alcohol conjugated with temozolomide (TMZ).
地址 Woodland Hills CA US