摘要 |
<p>PROBLEM TO BE SOLVED: To provide a novel compound which is a FGF receptor (FGFR) inhibitor which is a receptor tyrosine kinase of fibroblast growth factor (FGF).SOLUTION: There is provided a pyridine derivative represented by the formula (IA) or a pharmaceutically acceptable salt thereof. In the formula (IA), n is 0 to 2, A is an arylene group or a heteroarylene group, G is a single bond, an oxygen atom or -CH-, E is a nitrogen-containing non-aromatic hetero ring, Ris an alkoxy group, an alkoxyalkoxy group or the like, Ris H, a halogen atom, a hydroxyl group, an alkyl group, a hydroxyalkyl group, a nitrogen-containing non-aromatic hetero ring group or the like, Ris H, an alkyl group, an alkoxy group or the like, Ris a Calkyl group, where the Ror Ris not H when E is an azetidine ring and the Ror Rexists on a nitrogen atom of the azetidine ring.</p> |