发明名称 METHODS FOR TREATING A SUSPENSION OF MONONUCLEAR CELLS TO FACIILTATE EXTRACORPOREAL PHOTOPHERESIS
摘要 A method for performing a photopheresis procedure is provided comprising collecting MNCs in a suspension comprising RBCs and plasma and lysing the red blood cells in the solution, preferably by combining the suspension with a solution to cause lysis. In one example, the solution for causing lysis of the red blood cells comprises ammonium chloride, and the suspension including the ammonium chloride is incubated to cause lysing. After lysing, the suspension may be washed to remove plasma and hemoglobin freed by the lysis of the red blood cells, and an ultraviolet light activated substance is added to the suspension. The suspension is then irradiated with ultraviolet light.
申请公布号 US2014370491(A1) 申请公布日期 2014.12.18
申请号 US201313916854 申请日期 2013.06.13
申请人 FENWAL, INC. 发明人 Radwanski Katherine
分类号 A61M1/36 主分类号 A61M1/36
代理机构 代理人
主权项 1. A method of extracorporeal photopheresis of mononuclear cells comprising: collecting a suspension of mononuclear cells containing red blood cells; adding a lysing agent to the suspension; incubating the suspension to lyse the red blood cells; removing from the suspension hemoglobin freed by the lysing of the red blood cells; adding an ultraviolet light activated substance to the suspension; and irradiating the suspension with ultraviolet light.
地址 Lake Zurich IL US