THERMAL TREATMENT OF ACNE WITH NANOPARTICLES WITH COATINGS THAT FACILITATE SELECTIVE REMOVAL FROM THE SKIN SURFACE

摘要

Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of thermal treatment of acne with nanoparticles with coatings that facilitate selective removal from the skin surface are disclosed.

主权项

1. A method for performing thermoablation, comprising the steps of contacting a target tissue region of a mammalian subject with a composition comprising a plurality of plasmonic nanoparticles under conditions such that an effective amount of the plasmonic nanoparticles localize to a domain of the target tissue region; and exposing the target tissue region to energy delivered from a nonlinear excitation surface plasmon resonance source in an amount effective to induce thermoablation of the domain of the target tissue region, wherein the size of the nanoparticle is about 0.1 nm to about 50,000 nm in at least one dimension.