主权项 |
1. A method for performing thermoablation, comprising the steps of contacting a target tissue region of a mammalian subject with a composition comprising a plurality of plasmonic nanoparticles under conditions such that an effective amount of the plasmonic nanoparticles localize to a domain of the target tissue region; and exposing the target tissue region to energy delivered from a nonlinear excitation surface plasmon resonance source in an amount effective to induce thermoablation of the domain of the target tissue region, wherein the nanoparticle comprises a coat on a surface of the nanoparticle, wherein the coat comprises a biorecognitive material, bioactive material, biological material, biocide material, dielectric material, chemorecognitive material, chemical active material, polymer, environmentally sensitive polymer, fluorescent marker, hydrogel, metal, semiconductor, dielectric, or combination thereof. |