摘要 |
PROBLEM TO BE SOLVED: To provide inexpensive, multi-lane plastic biochips capable of performing focused nucleic acid analysis at high resolution and with a high signal to noise ratio, and methods of using such chips.SOLUTION: Plastic electrophoresis separation chips 100 are provided comprising a plurality of microfluidic channels 106 and a detection window 107, where the detection window 107 comprises a thin plastic, and the detection window 107 comprises a detection region of each microfluidic channel 106. Such chips 100 can be bonded to a support, and an aperture 107 is provided in the support to allow laser induced fluorescence detection of samples in the electrophoresis chip 100 at the thin plastic detection window 107. Further, methods for electrophoretically separating and detecting a plurality of samples on the plastic electrophoresis separation chip 100 are described. |