BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS
摘要
The present invention provides compounds of Formula I or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders. Also provided are pharmaceutical compositions containing compounds of the present invention.
申请公布号
WO2014201173(A1)
申请公布日期
2014.12.18
申请号
WO2014US41998
申请日期
2014.06.11
申请人
AMGEN INC.
发明人
WEISS, MATTHEW;DIMAURO, ERIN F.;DINEEN, THOMAS;GRACEFFA, RUSSELL;GUZMAN-PEREZ, ANGEL;HUANG, HONGBIN;KREIMAN, CHARLES;MARX, ISAAC E.;NGUYEN, HANH NHO;PETERSON, EMILY;DEAK, HOLLY L.