TISSUE STRUCTURE AND MANUFACTURING METHOD THEREFOR

摘要

Provided are a tissue structure that comprehensively reproduces the genetic pattern of mature cells, and a manufacturing method therefor. The tissue structure is obtained by cocultivating one kind of cell and/or factor, which is selected from a group consisting of vascular cells, mesenchymal cells, factors secreted from vascular cells, factors secreted from mesenchymal cells, and factors secreted by the co-existence of vascular cells and mesenchymal cells, with stem cell-derived endodermal, ectodermal or mesodermal cells. The tissue structure is configured from living tissue for which the values assayed for multiple functions using Pearson product-moment correlation coefficients are closer to values for cells or living tissue collected from a mature body than cells or living tissue collected from a fetus.