| 发明名称 |
INTERMEDIATES FOR THE PREPARATION OF BIVALENT SMAC MIMETICS |
| 摘要 |
The invention relates to bivalent mimetics of Smac which function as inhibitors of Inhibitor of Apoptosis Proteins. The invention also relates to the use of these mimetics for inducing apoptotic cell death and for sensitizing cells to inducers of apoptosis. |
| 申请公布号 |
PT2019671(E) |
申请公布日期 |
2014.12.18 |
| 申请号 |
PT20070794581T |
申请日期 |
2007.05.04 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
SHAOMENG WANG;YUEFENG PENG;HAIYING SUN;QIAN CAI;SU QIU;DONGGUANG QIN;ZANETA NIKOLOVSKA-COLESKA |
| 分类号 |
C07D487/04;A61K31/395;A61K31/407;A61K31/4192;A61K31/496;A61K38/19;C07D519/00 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
