| 发明名称 |
ESTRADIOL FORMULATIONS AND THERAPIES |
| 摘要 |
Estrogen and progesterone replacement therapies are provided herein. Among others, the following formulations are provided herein: solubilized estradiol without progesterone; micronized progesterone without estradiol; micronized progesterone with partially solubilized progesterone; solubilized estradiol with micronized progesterone; solubilized estradiol with micronized progesterone in combination with partially solubilized progesterone; and solubilized estradiol with solubilized progesterone. |
| 申请公布号 |
US2014370084(A1) |
申请公布日期 |
2014.12.18 |
| 申请号 |
US201314106655 |
申请日期 |
2013.12.13 |
| 申请人 |
TherapeuticsMD, Inc. |
发明人 |
Bernick Brian A.;Cacace Janice Louise;Persicaner Peter H.R.;Irani Neda;Amadio Julia M. |
| 分类号 |
A61K31/565 |
主分类号 |
A61K31/565 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising solubilized estradiol and a solubilizer comprising a medium chain oil, wherein the estradiol is at least 80% solubilized in the solubilizer, wherein the medium chain oil comprises substantially C6-C12 fatty acid esters, and wherein the composition is for oral administration. |
| 地址 |
Boca Raton FL US |
