发明名称 |
COMPOSITION FOR TREATING AND/OR DIAGNOSING COLORECTAL CANCER, AND USE THEREFOR |
摘要 |
The present invention treats colorectal cancer by using a composition containing an miR-31 inhibitor. The present invention diagnoses on the basis of the amount of miR-31 expression in a biological sample derived from a colorectal cancer patient. The present invention prepares a colorectal-cancer cell containing miR-31 or an miR-31 mimic, and screens a drug for treating colorectal cancer by using this colorectal-cancer cell. As a result, the present invention provides a technique for treating and/or diagnosing colorectal cancer having KRAS or BRAF mutations. |
申请公布号 |
WO2014200065(A1) |
申请公布日期 |
2014.12.18 |
申请号 |
WO2014JP65615 |
申请日期 |
2014.06.12 |
申请人 |
SAPPORO MEDICAL UNIVERSITY |
发明人 |
NOSHO, KATSUHIKO;SUZUKI, HIROMU;YAMAMOTO, HIROYUKI;SHINOMURA, YASUHISA |
分类号 |
A61K45/00;A61K31/7088;A61K39/395;A61P1/00;A61P35/00;A61P43/00;C12N15/115;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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