发明名称 |
MACROCYCLIC UREA DERIVATIVES AS INHIBITORS OF TAFIA, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS |
摘要 |
The present invention relates to macrocydic urea derivatives of the formula I (I) in which R1, R2, R3, V and Y are as defined below. The compounds of the formula I are inhibitors of the enzyme TAFIa (activated thrombin-activatable fibrinolysis inhibitor). The invention further relates to the process for the preparation of the compounds of formula I and to the use thereof as medicaments. |
申请公布号 |
CA2914533(A1) |
申请公布日期 |
2014.12.18 |
申请号 |
CA20142914533 |
申请日期 |
2014.06.05 |
申请人 |
SANOFI |
发明人 |
EVERS, ANDREAS;KALLUS, CHRISTOPHER;WAGNER, MICHAEL;WEHLAN, HERMUT |
分类号 |
C07D413/12;A61K31/553;A61P7/00;C07D273/01 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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