发明名称 |
INTERLEUKIN-10 COMPOSITIONS AND USES THEREOF |
摘要 |
Interleukin-10 muteins and other interleukin-10 - related molecules are described, as well as methods of identifying interleukin-10 muteins and other interleukin-10 - related molecules. Also described herein are modifications of the foregoing, which modifications may enhance a property (e.g., half-life) of the muteins or other molecules compared to human interleukin-10. Particular interleukin-10 muteins and related molecules have comparable immunogenicity to human interleukin-10 and/or bioactivity at least comparable to human interleukin-10. Pharmaceutical compositions and methods of use are also described herein. |
申请公布号 |
WO2014176373(A3) |
申请公布日期 |
2014.12.18 |
申请号 |
WO2014US35201 |
申请日期 |
2014.04.23 |
申请人 |
ARMO BIOSCIENCES, INC. |
发明人 |
MCCAULEY, SCOTT;VAN VLASSELAER, PETER |
分类号 |
C40B40/10;A61K38/00;G01N33/00 |
主分类号 |
C40B40/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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