SYSTEMS AND METHODS FOR DETERMINING BIOMECHANICAL PROPERTIES OF THE EYE FOR APPLYING TREATMENT

摘要

A system for determining biomechanical properties of corneal tissue includes a light source configured to provide an incident light and a confocal microscopy system configured to scan the incident light across a plurality of cross-sections of corneal tissue. The incident light is reflected by the corneal tissue as scattered light. The system also includes a filter or attenuating device configured to block or attenuate the Rayleigh peak frequency of the scattered light, a spectrometer configured to receive the scattered light and process frequency characteristics of the received scattered light to determine a Brillouin frequency shift in response to the Rayleigh peak frequency being blocked or attenuated by the filter or attenuating device, and a processor configured to generate a three-dimensional profile of the corneal tissue according to the determined Brillouin frequency shift. The three-dimensional profile provides an indicator of one or more biomechanical properties of the corneal tissue.

主权项

1. A system for measuring biomechanical properties of the eye to at least one of plan, implement, or assess treatments of the eye, the eye having an iris and a cornea, the system comprising:
a biomechanical measurement system, including:
a light source configured to provide an incident light,a confocal microscopy system configured to direct the incident light at a plurality of sections of the cornea, the incident light being scattered by the plurality of sections of the corneal tissue, anda spectrometer configured to receive the scattered light and process frequency characteristics of the received scattered light to measure a Brillouin frequency shift in the scattered light, the biomechanical measurement system being configured to generate biomechanical data based on the measured Brillouin frequency shift; a corneal topography measurement system configured to measure a corneal topography of the eye and generate corneal topography data indicative of the measured corneal topography; an iris imaging system configured to image the iris and generate iris image data indicative of the imaged iris; and one or more processors communicatively coupled to the biomechanical system, the corneal topography system, and the iris imaging system, the one or more processors including a processor clock; and one or more memory devices storing instructions that, when executed by the one or more processors, cause the one or more processors to:
generate time stamp data, based on the processor clock, for each of the biomechanical data, the corneal topography data, and the iris image data;store the biomechanical data with the associated time stamp data in the one or more memory devices;store the corneal topography data with the associated time stamp data in the one or more memory devices;store the iris image data with the associated time stamp data in the one or more memory devices;for each of the biomechanical data, determine which of the iris image data has the same associated time stamp data;for each of the corneal topography data, determine which of the iris image data has the same associated time stamp data;generate three-dimensional voxel data by correlating each of the biomechanical data with each of the corneal topography data determined to have the same associated iris image data, each of the three-dimensional voxel data including an indication of at least one of the biomechanical data, at least one of the corneal topography data, and at least one of the iris image data.