发明名称 |
Immunoglobulin Chimeric Monomer-Dimer Hybrids |
摘要 |
The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention. |
申请公布号 |
AU2012200470(B2) |
申请公布日期 |
2014.12.18 |
申请号 |
AU20120200470 |
申请日期 |
2012.01.27 |
申请人 |
BIOGEN IDEC HEMOPHILIA INC. |
发明人 |
PETERS, ROBERT T.;MEZO, ADAM R.;RIVERA, DANIEL S.;BITONTI, ALAN J.;STATTEL, JAMES M.;LOW, SUSAN C. |
分类号 |
C07H21/04;C07K1/02;C07K1/06;C07K1/10;C07K1/107;C07K16/00;C07K16/46;C12P21/00 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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