摘要 |
PROBLEM TO BE SOLVED: To provide treatment of acute exposure and diseases caused by biodefense pathogens.SOLUTION: Macrolide is represented by formula I. In the formula I, R10 is H or acyl; X is H; Y is OR7; R7 is monosaccharide, disaccharide or the like; X and Y are taken together with the attached carbon to form carbonyl; V is C(O) or the like; W is H, F or the like; A is CH2, C(O) or the like; B is (CH2)n, in which n is an integer of 0 to 10 or B is an unsaturated carbon chain; and C is hydrogen, hydroxy or the like. |