PAMAM, SPACER MOLECULE AND CAFESTOL POLYMERS

摘要

The present invention is directed to a polymeric compound with a size in a nanometric scale, useful as a biocompatible carrier for the transport and delivery of active agents into a fish, insect, animal, reptile, bird, human, or plant, wherein said polymeric compound comprises PAMAM (polyamidoamine) dendrimers, a spacer molecule, and cafestol, wherein the polymeric compound of the invention comprises a structure of the kind (cafestol-PAMAM derivative)2-spacer molecule. Use of the compound as a biocompatible carrier for transport and delivery of antithrombotic active agents is disclosed. Procedures for obtaining a polymeric compound comprising the activation of cafestol, activation of polyethylene glycol, and formation of cafestol-PAMAM-PEG-PAMAM-cafestol are also disclosed.

主权项

1. Polymeric compound in nanometric scale for using as a biocompatible carrier for the transport and delivery of active agents in a fish, insect, animal, reptile, bird, human, or plant in need thereof, wherein the polymer comprises PAMAM (polyamidoamine) dendrimers, a spacer molecule, and cafestol.