<p>The present invention provides a method of treating nasopharyngeal cancer with a proteasome inhibitor of formula (7). The invention also provides a method of treating a patient with nasopharyngeal cancer based on elevated expression levels of NFkB, as measured by a H-score of the patient's nasopharyngeal cancer tumor sample using a“NFkB p65 IHC assay. The invention also provides a method of determining whether to treat a patient with the compound of formula (I) based on the level of NFkB p65 in the patient's nasopharyngeal cancer tumor sample.</p>
申请公布号
EP2812338(A1)
申请公布日期
2014.12.17
申请号
EP20130740996
申请日期
2013.01.23
申请人
MILLENNIUM PHARMACEUTICALS, INC.
发明人
BLAKEMORE, STEPHEN, J.;DI BACCO, ALESSANDRA, M.;MULLIGAN, GEORGE, J.