筋萎縮性側索硬化症および関連する運動ニューロン疾患の診断、処置および予防のための、ＦＵＳ／ＴＬＳベースの化合物および方法

摘要

The invention provides novel FUS/TLS nucleic acids and proteins that comprise one or more genetic markers (for example, single nucleotide polymorphisms) and methods of use thereof including methods relating to the diagnosis of ALS or other related motor neuron disease by virtue of the presence of the mutant FUS/TLS sequence(s).