EFFERVESCENT FORMULATIONS OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS

摘要

An effervescent formulation comprising a low-melting non-steroidal anti-inflammatory drug (NSAID) and an effervescent couple comprising: (a) a granular composition comprising a plurality of solidified melt granules of the (NSAID) with either an acidic or a basic component of the effervescent couple uniformly dispersed therein; and (b) an extra-granular composition comprising the other of the basic or acidic component of the effervescent couple.