| 摘要 |
Process to combine two molecules through inverse electron demand Diels-Alder-reaction comprises reacting diazines, triazines or tetrazines containing electron withdrawing substituents on a ring as diene component, where the electron withdrawing groups are halogen, carbonyl group containing derivatives, cyano, sulfur- or phosphorus derivative, with an isolated double bond- and/or triple bond in a (hetero)carbocyclic ring or an isolated olefinic double- and/or a triple bond in a hydrocarbon chain which optionally contains hetero atoms, as dienophile component. Process to combine two molecules through inverse electron demand Diels-Alder-reaction comprises reacting diazines, triazines or tetrazines containing electron withdrawing substituents on a ring as donating component, where the electron withdrawing groups are halogen, carbonyl group containing derivatives such as -COOR or C(O)NR 2, CX 3, cyano, sulfur derivatives such as SO 2R or SO 3R, or phosphorus derivative such as PR 2, with an isolated double- and/or triple bond in a (hetero)carbocyclic ring or an isolated olefinic double- and/or a triple bond in a hydrocarbon chain which optionally contains hetero atoms, as dienophile component. R : alkyl, aryl, hetero cyclic ring (all optionally substituted by alkyl, OH, SH, halo, aryl, heterocyclic, nitro, carboxyamido or amino) or H; and X : halo. |
