| 发明名称 |
Process and intermediates for the preparation of aspartic acetal caspase inhibitors |
| 摘要 |
<p>The invention relates to
a process of producing a compound of
comprising purifying a mixture of
wherein R 8 is a protecting group, and purifying includes chromatographing, selectively crystallizing, or dynamically crystallizing the mixture.</p> |
| 申请公布号 |
EP2399915(B1) |
申请公布日期 |
2014.12.17 |
| 申请号 |
EP20110178126 |
申请日期 |
2005.03.11 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
TANOURY, GERALD J.;CHEN, MINZHANG;JONES, ANDREW D.;NYCE, PHILIP L.;TRUDEAU, MARTIN;GUERIN, DAVID J.;SNOONIAN, JOHN R. |
| 分类号 |
C07D405/12;C07B43/04;C07B57/00 |
主分类号 |
C07D405/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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