发明名称 |
TOXIN DETECTION METHOD |
摘要 |
According to the present invention, an antibody against a Panton-Valentine leukocidin toxin contained in Staphylococcus aureus, a method and a kit for detecting the toxin with the use of the antibody, and a pharmaceutical composition containing an antibody against a Panton-Valentine leukocidin toxin for treating PVL infection caused by Staphylococcus aureus containing PVL are provided. Also, an antibody which is capable of binding to Panton-Valentine leukocidin F and has no cross-reactivity to LukD and/or HlgB and an antibody which is capable of binding to Panton-Valentine leukocidin S and has no cross-reactivity to at least one of LukE, HlgC, and HlgA are provided. |
申请公布号 |
CA2656756(C) |
申请公布日期 |
2014.12.16 |
申请号 |
CA20072656756 |
申请日期 |
2007.07.03 |
申请人 |
JUNTENDO UNIVERSITY SCHOOL OF MEDICINE;DENKA SEIKEN CO., LTD. |
发明人 |
OHISHI, KANENARI;BABA, TADASHI;HIRAMATSU, KEIICHI;NAKATOMI, YASUO |
分类号 |
C07K16/12;A61K39/09;A61K39/395;A61P31/04;A61P37/04;G01N33/53;G01N33/569 |
主分类号 |
C07K16/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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