Microfluidic element for analyzing a liquid sample

摘要

A microfluidic element for analyzing a bodily fluid sample for an analyte contained therein is provided, the element having a substrate, a channel structure that is enclosed by the substrate, and a cover layer, and is rotatable around a rotational axis. The channel structure of the microfluidic element includes a feed channel having a feed opening, a ventilation channel having a ventilation opening, and at least two reagent chambers. The reagent chambers are connected to one another via two connection channels in such a manner that a fluid exchange is possible between the reagent chambers, one of the reagent chambers having an inlet opening, which has a fluid connection to the feed channel, so that a liquid sample can flow into the rotational-axis-distal reagent chamber. At least one of the reagent chambers contains a reagent, which reacts with the liquid sample.

主权项

1. A microfluidic element for analyzing a liquid sample comprising a substrate, a channel structure enclosed by the substrate, and a cover layer, wherein
the microfluidic element is rotatable around a rotational axis; the channel structure includes a feed channel having a feed opening, a ventilation channel having a ventilation opening, and at least two reagent chambers; the reagent chambers are directly connected to one another via two separate connection channels in such a manner that a fluid exchange is possible between the reagent chambers,
one of the reagent chambers has an inlet opening, which has a fluid connection to the feed channel, so that a liquid sample can flow into the rotational-axis-distal reagent chamber, which, of the two reagent chambers, is positioned farther away from the rotational axis, andat least one of the reagent chambers contains a reagent, which reacts with the liquid sample that is introduced into such reagent chamber.