发明名称 Three-dimensional derivation of a proximal isokinetic shell of a proximal flow convergence zone and three-dimensional PISA flow measurement
摘要 The invention relates to a device and to a method for adaptive three-dimensional derivation of a proximal isokinetic shell of a proximal flow convergence zone that forms in an observation area in a moving fluid, wherein the magnitude of the velocity of the fluid at each point of the proximal isokinetic shell is identical and equal to a velocity reference value, the method including: a) preparing locally distributed velocity measurements in a surrounding area of the observation area, the measurements representing at least one directional component of the local velocity of the fluid in a respective measurement direction, b) preparing an approximation surface as an initial proximal isokinetic shell) in such a way that the entire flow, at least substantially, in the flow convergence zone penetrates the approximation surface, c) establishing a plurality of approximation points on the approximation surface, d) determining the respective velocity measurements at the respective approximation points, e) calculating a corrected velocity (vkkJ) at each approximation point as a function of the velocity measurement indicated there, the respective measurement direction; and the respective surface normal, f) determining a correction direction by comparing the corrected (vkkJ) velocity with the velocity reference value, g) optionally shifting the approximation points in the respective correction direction to new positions, h) acquiring a new approximation surface such that the same at least approaches the new positions of the approximation points, and i) repeating steps c) through h) until the change of the new approximation surface is sufficiently minimal compared to the old approximation surface.
申请公布号 US8911375(B2) 申请公布日期 2014.12.16
申请号 US200913125617 申请日期 2009.10.19
申请人 Tomtec Imaging Systems GmbH 发明人 Schreckenberg Marcus;Schummers Georg
分类号 A61B8/06 主分类号 A61B8/06
代理机构 Cantor Colburn LLP 代理人 Cantor Colburn LLP
主权项 1. A method of measuring flow rate of blood in human body using a color Doppler ultrasound device and an adaptive three-dimensional derivation of a proximal isokinetic shell of a proximal flow convergence zone that forms in an observation area in the blood, wherein magnitude of a velocity of the blood at each point of the proximal isokinetic shell is the same, the method comprises the steps of: a) obtaining locally distributed velocity measurements in an area surrounding the observation area using the color Doppler ultrasound device, said velocity measurements representing at least one directional component of the local velocity of the blood in a respective measurement direction, b) selecting one of the velocity values obtained in step (a) as a velocity reference value, c) preparing an approximation surface as an initial proximal isokinetic shell in such a way that the entire flow, at least substantially, in the flow convergence zone penetrates the approximation surface, d) establishing a plurality of approximation points on the approximation surface, e) determining a velocity measurement vkj at each approximation point, f) calculating a corrected velocity vkkj at each approximation point as a function of the velocity measurement at the respective approximation point, the respective measurement direction; and a surface normal at the respective approximation point, g) determining a correction direction by comparing the corrected velocity with the velocity reference value, h) shifting the approximation points in the respective correction direction to new positions, if necessary, i) acquiring a new approximation surface such that the new approximation surface at least approaches the new positions of the approximation points, and j) repeating steps d) through i) until the change of the new approximation surface is sufficiently minimal compared to the old approximation surface, k) determining surface area of the new approximation surface acquired in step (j), l) calculating the flow rate of blood by multiplying the surface area of the new approximation surface by the velocity reference value.
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