Ventilation sensor rate response normalization and calculation

摘要

A cardiac rhythm management (CRM) device can extract ventilation information from thoracic impedance or other information, and adjust a delivery rate of the CRM therapy. A tidal volume of a patient is measured and used to adjust a ventilation rate response factor. The measured tidal volume can optionally be adjusted using a ventilation rate dependent adjustment factor. The ventilation rate response factor can also be adjusted using a maximum voluntary ventilation (MVV), an age predicted maximum heart rate, a resting heart rate, and a resting ventilation determined for the patient. In various examples, a global ventilation sensor rate response factor (for a population) can be programmed into the CRM device, and automatically tailored to be appropriate for a particular patient.

主权项

1. A cardiac rhythm management system comprising:
a signal processor configured to:
measure a tidal volume of a patient;adjust the measured tidal volume using a ventilation rate dependent adjustment factor to generate a ventilation rate compensated tidal volume, wherein the ventilation rate dependent adjustment factor is configured to compensate for a filter non-ideality in the signal processor, andadjust a ventilation sensor rate response factor using information determined from the ventilation rate compensated tidal volume; and a controller, coupled to the signal processor, the controller configured to calculate a ventilation sensor driven pacing rate, including applying the adjusted ventilation sensor rate response factor to a deviation in an observed ventilation sensor output from a baseline.