| 发明名称 | Stem cell factor inhibitor | ||
| 摘要 | Provided herein are methods, compositions, and uses relating to inhibitors of stem cell factor. For example, provided herein are antibodies targeting stem cell factor and methods for treating fibrotic and tissue remodeling diseases. | ||
| 申请公布号 | US8911729(B2) | 申请公布日期 | 2014.12.16 |
| 申请号 | US201213347459 | 申请日期 | 2012.01.10 |
| 申请人 | The Regents of The University of Michigan | 发明人 | Lukacs Nicholas W.;Dolgachev Vladislav;Kunkel Steven L.;Hogaboam Cory M.;Phan Sem H. |
| 分类号 | A61K39/40;A61K39/395;C07K16/22;C07K16/24;A61K39/00 | 主分类号 | A61K39/40 |
| 代理机构 | Casimir Jones, S.C. | 代理人 | Isenbarger Thomas A.;Casimir Jones, S.C. |
| 主权项 | 1. A method of treating a disease that is a fibrotic disease or a tissue remodeling disease comprising administering a therapeutically effective amount of an anti-stem cell factor monoclonal antibody that specifically binds to SEQ ID NO: 1 or an antigen-binding fragment of said anti-stem cell factor monoclonal antibody to a subject with or at risk for a disease that is a fibrotic disease or a tissue remodeling disease. | ||
| 地址 | Ann Arbor MI US | ||